The Ebola outbreak of 2014 (Contd.)

Following up on the previous post here are some more detail on the recent Science paper along with a round-up of "what do we know, what have we learned" thus far. The Gire et al paper in Science was huge amount of work and a giant collaborative research effort. Being a computational biology researcher, I [...]

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Solving the Ebola Virus Genome and Identifying Possible Diagnosis

If you have ever played the card game Killer Bunnies and your Bunnies in the Bunny circle have died because of the Level 11 Weapon of Ebola Virus you want to read this. Research community is making strides to understand whether the virus is adapting to its host or changing as it spreads through the [...]

How recent are rare variants?

The Department of Genome Sciences at the University of Washington in Seattle, in a multi-institutional effort sequenced 15,336 genes for the NHLBI sponsored ESP project from a total of 6515 individuals of European American and African American descent.To identify approaches for disease-gene discovery, its important to understand evolutionary history of homosapiens and identify the age [...]

The common story of rare variants..

NGS comes to the aid of researchers to find answers for herited complex traits and diseases, paving a path towards the ‘personalized medicine era’. Whole-exome sequencing (WES) has been deployed for identifying rare variants associated with complex diseases and is providing a philip for further research and insight. Common variants that were identified through Genome [...]

Vaccine Wars or not..

Attended a talk on 'Vaccine Wars in the 21st Century' by Dr. Gregory Poland from the Mayo Clinic at the University of Minnesota Rochester Campus Major points Poland covered were on how we live in an age where information is confused with knowledge. Broadly he went over how the immunization rates are dropping and anti [...]